Acetyl-L-carnitine is a vital amino acid derivative known to fuel the body's cellular energy production and bolster nerve function. Predominantly useful for brain function, mood enhancement, nerve health, and cognitive prowess, it also stands out as a favorite among fitness enthusiasts for its potential in increasing energy levels.
The “carnitine shuttle” is a key mechanism in the production of energy in the mitochondria, the energy-producing organelles in our cells.
The need to know
What are the benefits?
Neurological brain supporter
Promotes brain function and energy production
Supports nerve function
May also be beneficial for fertility
Acetyl-L-carnitine plays a pivotal role in energy production, acting as a carrier that transports fatty acids to the mitochondria, the cell's powerhouse in a mechanism known as the “carnitine shuttle”.
Here, these fats are burned for energy.
Beyond energy production, acetyl-L-carnitine stands out because it can cross the blood-brain barrier. This enables it to have a direct positive effect on brain cells, supporting neuron health and neurotransmitter function.
Its potential benefits for fertility arise from its role in sperm cell energy production in men, while for women, it may enhance the quality of the oocytes.
Note: when taking very high doses of carnitine, over 5000mg per day, levels of TMAO can increase which is linked to heart health. This increase can be ameliorated by combining with silymarin which normalizes levels.
How will I know its working?
Noticeable improvement in cognitive clarity and mood stabilisation.
Enhanced energy levels, especially during workouts or daily tasks.
For those monitoring fertility, potential improvement in fertility metrics over consistent use.
When to take it?
Take 1 capsule daily with food and water, unless specified otherwise on the sachet.
Serving Size 1 Vegetarian Capsule
Per Serving% Daily
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.
Brown Rice Flour, Gelatine
Did you know?
Acetyl-L-carnitine can cross the blood-brain barrier, directly benefiting brain cells - a trait not shared by all amino acids.
While present in foods, the highest concentrations are found in red meats. Hence, vegans or those on calorie-restricted diets may require supplementation.
Aside from its brain and energy benefits, it's also researched for its potential in supporting auditory health, possibly aiding in conditions like age-related hearing loss.
Publications you might find interesting
Want to go a bit deeper?
The latest research
1. Carter, A.L., and O’Brien, P.D. "Role of Acetyl-L-carnitine in the Treatment of Diabetic Peripheral Neuropathy." *Journal of Clinical Neuroscience* 45 (2017): 123-129.
2. Malaguarnera, M., et al. "Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue." *Archives of Gerontology and Geriatrics* 46.2 (2008): 181-190.
3. Cavallini, G., et al. "Carnitine versus androgen administration in the treatment of sexual dysfunction, depressed mood, and fatigue associated with male aging." *Urology* 63.4 (2004): 641-646.
4. Traina, G. "The neurobiology of acetyl-L-carnitine." *Frontiers in bioscience (Landmark edition)* 21 (2016): 1314-1329.
5. Lohninger, S., et al. "Effects of a combined treatment with micronutrient supplements and swimming exercise on the composition of fatty acids in brain and peripheral nerves in the aged rat." *Neurochemical research* 29.1 (2004): 225-234.
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