Longevity

More of your best days

 

Restore Energy Production

NAD levels drop to 50% by middle age. Maintaining energy production and NAD levels is crucial to organ function and longevity pathways.

Maintain Brain Function

Omega-3 for grey matter, nootropics for cognition and memory, neurotransmitter support and protection from inflammation. All are key in protecting from neurodegeneration.

DNA and epigenentic stability

Healthy DNA is supported by activating sirtuin pathways, autophagy and mitophagy. Key enzyme pathways in the redox system keeps cells healthy.

Holistic health

Sleep, diet, exercise and stress control. Optimal digestion and gut health are all key in reducing the accelerators of ageing.

Functional Longevity

Build a solid foundation.

Before optimising and boosting longevity pathways the fastest, easiest and most substantial gains can be made by optimising the basics. that means checking for deficiencies in vitamins D, B12, folate, and iron. They are essential for normal metabolic, hormonal and mitochondrial function, the foundations of Longevity. See our nutrient blood test.

Get on top of any gut issues. Check out The IBS-SIBO solution.

Or get going with our leading longevity supplements such as NMN, Trans-resveratrol, Quercetin, Urolithin A and Spermidine.

Dr Geoff Mullan recommends our longevity pack containing a combination of synergistic longevity supplements.

If you're looking for something specific you can build your own stack and we will build this for you, build your own Longevity stack.

Our top longevity supplements

  1. NMN's critical role in promoting cellular health and longevity is well-established.
  2. Trans-resveratrol has the ability to enhance lifespan via sirtuin activation is backed by substantial research.
  3. Urolithin A drives cleansing and recycling of mitochondria to boost muscle strength.
  4. Spermidine increases autophagy, a key role in renewal and longevity.
  5. L-glutathione. The antioxidant and anti-inflammatory capabilities of glutathione are fundamental for age-defence.
  6. Quercetin acts as an antioxidant, mitigating oxidative stress, reducing inflammation, and potentially enhancing mitochondrial function for longevity benefits.

Advanced longevity supplements

  • NMN Pure

    A key molecule to energy production, NAD, drops to 50% by middle age. Reversing this drop leads to better function today and longevity.

    NMN Pure 

  • Urolithin A Pure

    The energy production factories in our cells, mitochondria, are key to healthy function. Urolithin A stimulates renewal of mitochondria leading to a reversal of muscle loss and improved athletic performance.

    Urolithin A Pure 

  • Spermidine Pure

    Deep fasting induces autophagy and the removal of unhealthy cells. This process can also be induced by spermidine.

    Spermidine Pure 

Ready-to-go longevity stacks

From the experts

Longevity stack

£85.00

This Longevity Stack is a potent NAD booster and also great for boosting energy.

  • NMN 500MG
  • Trans Resveratrol 500MG
  • Quercetin 400MG
  • CoQ10 100MG
  • D3 4000 IU
  • K2 (MK7) 250 MCG
  • Methylated B Complex
  • Full details→

Prof. Sinclair Stack

£115.00

Prof. David Sinclair is a world-leading Longevity expert. This is what is in his stack. Note he also takes metformin, statins and aspirin.

  • NMN 1000MG
  • Trans Resveratrol 500MG
  • CoQ10 100MG
  • Alpha Lipoic Acid 300mg
  • D3 4000 IU
  • K2 (MK7) 250 MCG
  • Full details →
MOST ADVANCED

Dr Geoff's Stack

£160.00

If you want all of our most advanced Longevity supplements in one this is the ultimate combination.

  • NMN 500MG
  • Urolithin A 500mg
  • Spermidine 700mg
  • Trans Resveratrol 500MG
  • CoQ10 100MG
  • D3 4000 IU
  • K2 (MK7) 250 MCG
  • Methylated B Complex
  • Full details→

Interested in our Doctor's selection?

Our medical team led by our Chief Medical Officer Dr Geoff Mullan has put together a pack of supplements that have synergistic effects based on both clinical experience and the latest research.

If some of the contents are already in your pack our AI will sort these out and only add the new ones. That allows you to merge different specialist packs without duplication.

Check out the full details of the Longevity pack.

Longevity

Longevity pack

Our longevity pack combines single high strength supplements into daily packs for your convenience. Contains NMN, trans-resveratrol, and more...

Longevity pack

Longevity and energy

Ultimate NAD booster

NMN Pure the NAD precursor with high strength trans-resreveratrol and querctin in easy single packs.

NAD booster

99% Independently tested

NMN pure

A molecule that can improve your energy levels and put a spring in your step whilst making you live longer. Add to you pack or buy now.

NMN Pure

Longevity Pack Improvement Timeline

Longevity is about adding more life to your days and feeling better today and tomorrow.

Month 1

Improved concentration. Calm, clear focus. Improved energy.

Month 2

Better exercise recovery. Reduced inflammation.

Month 3

Measurable improvements in blood markers and biometrics.

All the latest news

Links to the research

Bibliography

  1. Das A, Huang GX, Bonkowski MS, et al. Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging [published correction appears in Cell. 2019 Feb 7;176(4):944-945]. Cell. 2018;173(1):74-89.e20. doi:10.1016/j.cell.2018.02.008
  2. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016/j.redox.2019.101192
  3. Li YR, Li S, Lin CC. Effect of resveratrol and pterostilbene on aging and longevity. Biofactors. 2018;44(1):69-82. doi:10.1002/biof.1400
  4. Deng Z, Li Y, Liu H, et al. The role of sirtuin 1 and its activator, resveratrol in osteoarthritis. Biosci Rep. 2019;39(5):BSR20190189. Published 2019 May 10. doi:10.1042/BSR20190189
  5. Qi W, Qi W, Xiong D, Long M. Quercetin: Its Antioxidant Mechanism, Antibacterial Properties and Potential Application in Prevention and Control of Toxipathy. Molecules. 2022;27(19):6545. Published 2022 Oct 3. doi:10.3390/molecules27196545
  6. Deepika, Maurya PK. Health Benefits of Quercetin in Age-Related Diseases. Molecules. 2022;27(8):2498. Published 2022 Apr 13. doi:10.3390/molecules27082498
  7. Hofer SJ, Simon AK, Bergmann M, Eisenberg T, Kroemer G, Madeo F. Mechanisms of spermidine-induced autophagy and geroprotection. Nat Aging. 2022;2(12):1112-1129. doi:10.1038/s43587-022-00322-9
  8. Xu TT, Li H, Dai Z, et al. Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice. Aging (Albany NY). 2020;12(7):6401-6414. doi:10.18632/aging.103035
  9. Ryu D, Mouchiroud L, Andreux PA, et al. Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents. Nat Med. 2016;22(8):879-888.
  10. Totiger TM, Srinivasan S, Jala VR, et al. Urolithin A, a Novel Natural Compound to Target PI3K/AKT/mTOR Pathway in Pancreatic Cancer. Mol Cancer Ther. 2019;18(2):301-311. doi:10.1158/1535-7163.MCT-18-0464
  11. Liberal J, Carmo A, Gomes C, Cruz MT, Batista MT. Urolithins impair cell proliferation, arrest the cell cycle and induce apoptosis in UMUC3 bladder cancer cells. Invest New Drugs. 2017;35(6):671-681. doi:10.1007/s10637-017-0483-7
  12. Mavrodaris A, Lafortune L, Brayne CE. The future longevity: designing a synergistic approach for healthy ageing, sustainability, and equity. Lancet Healthy Longev. 2022;3(9):e584-e586. doi:10.1016/S2666-7568(22)00145-3

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