Advanced cholesterol home blood test: includes ApoB and Lipoprotein(a) - kit sold in person by partner

Advanced cholesterol home blood test: includes ApoB and Lipoprotein(a) - kit sold in person by partner

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    Advanced cholesterol test includes Apolipoprotein B and lipoprotein(a)

    The best cholesterol test is one that gives you an accurate understanding of your risk factors.

    Our advanced lipid and cholesterol test provides a more detailed analysis of cholesterol and its components, offering a clearer picture of heart disease risk than standard tests. This test is especially useful in identifying individuals at risk despite having normal cholesterol levels, as it delves into the size and density of cholesterol particles, which are critical factors in cardiovascular health.

    Read more about advanced lipid profiles here.

    Understanding cholesterol: the comprehensive advanced lipid test

    This advanced lipid panel includes ApoA, ApoB, Ratio ApoB/A1, Lipoprotein (a), Total Cholesterol, LDL, HDL, Triglycerides, Total Cholesterol: HDL ratio, Triglyceride: HDL ratio, LAR (LDL:ApoB ratio) estimation of LDL particle size

    Image of Dr Geoff Mullan Chief Medical Officer

    Advanced lipid profiles, from our experts to you

    Dr Geoff Mullan MBBS, BSc. MRCS, DO-HNS, AFMCP

    Chief Medical Director

    what is in this test

    Advanced lipid and cholesterol testing

    Apoliprotein B

    Each LDL particle, which carries cholesterol, has one ApoB protein. Measuring ApoB gives a true count of LDL particles in your blood. Since smaller LDL particles are more harmful than larger ones, knowing the number of particles can help assess cardiovascular risk more accurately than just measuring LDL cholesterol alone.

    • Importance: ApoB is found in LDL (low-density lipoprotein) and VLDL (very-low-density lipoprotein) cholesterol. It's essential for the transport and distribution of cholesterol. Since LDL is often labeled as "bad" cholesterol, ApoB serves as a marker for atherogenic particles – those that contribute to plaque buildup in arteries.
    • Insights: Elevated levels of ApoB are associated with an increased risk of cardiovascular disease, as they indicate a higher quantity of LDL particles, which can lead to plaque formation and arterial blockages.

    Apolipoprotein A (ApoA)

    ApoA is a component of HDL, the 'good' cholesterol. It helps remove cholesterol from the body. High levels of ApoA indicate a healthy cholesterol transport system and a lower risk of heart disease.

    • Importance: ApoA is a primary protein component of HDL (high-density lipoprotein) cholesterol, often referred to as "good" cholesterol. It plays a critical role in lipid metabolism, particularly in the removal of cholesterol from cells and its transport back to the liver for excretion.
    • Insights: Higher levels of ApoA are usually indicative of a healthier lipid profile and a lower risk of cardiovascular disease. This is because ApoA aids in the process of reverse cholesterol transport, which is protective against the development of atherosclerosis.

    ApoB/ApoA1 Ratio

    ApoB/ApoA1 Ratio:This ratio compares the amount of ApoB (bad cholesterol marker) to ApoA1 (good cholesterol marker). A higher ratio means there's more bad cholesterol relative to good cholesterol, indicating a greater risk for heart problems.Importance: This ratio compares the levels of ApoB and ApoA1, providing a balance between harmful and protective lipoproteins.

    • Insights: A higher ApoB/ApoA1 ratio is indicative of a higher concentration of atherogenic lipoproteins relative to protective ones, suggesting a heightened risk for atherosclerosis and cardiovascular diseases. It's a more comprehensive measure than looking at LDL or HDL alone.

    LDL-C/ApoB Ratio (LAR) particle size estimation

    This ratio helps estimate the size of LDL particles. Smaller, denser LDL particles are more harmful. A lower ratio suggests more small, dense LDL particles, indicating a higher risk of heart disease.

    • Importance: This ratio estimates the average size of LDL particles. It's a marker for the type of LDL particles present in the bloodstream – whether they are predominantly large and buoyant or small and dense.
    • Insights: A lower LAR suggests a greater proportion of small, dense LDL particles, which are more atherogenic and pose a higher risk for heart disease. Conversely, a higher ratio indicates larger, less atherogenic particles.

    Lipoprotein (a) [Lp(a)]

    Lp(a) is a type of cholesterol particle similar to LDL but with an added protein that increases the risk of heart disease. High levels of Lp(a) are mainly determined by genetics and are a strong indicator of heart disease risk.

    • Importance: Lp(a) is a variant of LDL cholesterol but with an additional protein, apolipoprotein(a). It's an independent risk factor for cardiovascular disease and is largely genetically determined.
    • Insights: Elevated levels of Lp(a) are concerning as they can contribute to the development of atherosclerosis, increasing the risk of heart attacks and strokes. Unlike other lipid markers, Lp(a) levels are not significantly affected by lifestyle changes and are more challenging to manage.

    Total Cholesterol, LDL, HDL, Triglycerides

    These are standard cholesterol measures. Total cholesterol is the overall amount of cholesterol, LDL is the 'bad' cholesterol, HDL is the 'good' cholesterol, and triglycerides are a type of fat in the blood. Together, they give a basic picture of heart disease risk. We use them to calculate risk factors with more advanced measurements.

    • Importance: These traditional markers provide an overall picture of blood lipid levels. Total cholesterol is the sum of all types of cholesterol; LDL is often labeled as bad cholesterol; HDL is known as good cholesterol due to its protective role; and triglycerides are a type of fat in the blood.
    • Insights: These values help assess the general risk of cardiovascular disease, but they don't provide specifics about particle size or the number of atherogenic particles, which are crucial for a more accurate risk assessment.

    Total Cholesterol: HDL Ratio and Triglyceride: HDL Ratio

    These ratios compare total cholesterol and triglycerides to HDL (good) cholesterol. Lower ratios are better, indicating a lower risk of heart disease.

    • Importance: These ratios offer a more nuanced view of the lipid profile by comparing levels of total cholesterol and triglycerides to HDL cholesterol.
    • Insights: Lower ratios are generally better. A high Total Cholesterol: HDL ratio or a high Triglyceride: HDL ratio suggests an unfavorable lipid profile, indicating a higher risk of cardiovascular disease.

    Manage your cholesterol risk naturally

    • Cholesterol levels start to rise from age 35

      • Cholesterol levels in humans tend to remain relatively stable during young adulthood but start to increase around the age of 20.
      • Interestingly, the average age at which cholesterol levels begin to significantly rise is around 40 to 45 years for men and 50 to 55 years for women.
      • The increase in cholesterol is partly due to changes in metabolism as we age. For men, the rise often occurs slightly earlier, coinciding with a gradual decline in testosterone levels.
      • For women, the increase is often seen post-menopause, when the protective effects of oestrogen on cholesterol levels diminish.
    • The 'Invisible' Influence of Genetics

      • While diet and lifestyle are well-known factors affecting cholesterol levels, genetics play a surprisingly strong role.
      • A condition called Familial Hypercholesterolemia (FH) can cause exceptionally high cholesterol levels, even in very young individuals and those leading healthy lifestyles.
      • What's fascinating is that FH is relatively common, affecting 1 in every 250 people worldwide, but many remain undiagnosed.
      • This genetic trait can significantly increase the risk of early heart disease if not managed properly.
    • The Statin Paradox: Why Dietary Changes Might Trump Medication

      • Statins, commonly prescribed for lowering cholesterol, are not without their challenges. One of the most compelling reasons to manage cholesterol through diet instead of statins is the potential for side effects and nutrient interactions.
      • Statins have been associated with a range of side effects, from mild issues like muscle pain and digestive problems to more serious concerns like increased risk of type 2 diabetes and liver damage.
      • The heart health twist: Statins can also reduce the body's levels of Coenzyme Q10 (CoQ10), a vital nutrient for heart health and muscle function. This reduction in CoQ10 can potentially contribute to the muscle aches commonly experienced by statin users. Ironically, while statins are used to protect heart health, the decrease in CoQ10 could counteract some of their beneficial effects.
    • Lifestyle

      Lifestyle and Diet Adjustments: A heart-healthy diet rich in fruits, vegetables, whole grains, and lean proteins can significantly reduce LDL cholesterol. Regular physical activity also plays a crucial role, with exercises like brisk walking, cycling, and swimming shown to improve cholesterol levels and heart health.

    • Managing Underlying Conditions

      Conditions like thyroid disorders, diabetes, and obesity can contribute to high cholesterol. Properly managing these conditions through medication, lifestyle changes, and regular check-ups can help keep cholesterol levels in check.

    • Supplemental Support

      Incorporating supplements can further aid in managing cholesterol levels. Notable ones include:

      • NMN (Nicotinamide Mononucleotide): Enhances cellular metabolism and energy production.
      • Alpha Lipoic Acid: Acts as an antioxidant and improves insulin sensitivity.
      • Berberine: Nature's metformin has a significant impact on cholesterol levels and reduce glucose production in the liver.
      • CoQ10 (Coenzyme Q10): Vital for heart health and energy production, especially beneficial for those on statins.
      • Omega-3 Fatty Acids: Found in fish oil supplements, they help reduce triglyceride levels and improve heart health.

    No finger pricks: use our needle free home blood collection device

    Track and measure

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    Personal dashboard

    Your results will be uploaded to your personal secure dashboard.

    You can track progress over time and optimise your essential nutrient status.

    Personal recommendations

    Your results will be integrated with your health assessment.

    One of our medical team will review these and make nutrition, lifestyle and supplement recommendations.

    Innovative blood collection device

    Use our innovative home collection device to make blood collection simple and easy to do at home.

    See the video below to see it in action.

    What do we measure?

    Total testosteron

    Test and track

    Track your levels on your personalised dashboard


    Get recommendations based on your results


    Increase your health and longevity

    frequently asked questions


    Does the blood test hurt?

    No, the blood test really is painless. It doesn't even use needles!

    When will I get my results?

    Results are back within 5 working days, but we can often do a lot quicker than that. The exception is omega 3 which needs to go to a specialist lab. and results can take a few weeks.

    Will you really send a video explaining my results at no extra cost?

    Yes! We make it simple to understand your results and recommendations by sending a video of a Doctor explaining them.

    Is humanpeople a registered and regulated company?

    Yes. Unlike a lot of other blood testing companies in the UK. humanpeople is registered with the CQC as a health and diagnostic company.

    That means we are reviewed and must follow strict UK guidelines on giving results and advice.

    The labs. we use are also regulated by CQC.

    You can check out our registration details here.

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