Alpha lipoic acid (ALA) is a potent antioxidant that is naturally found in various foods and has been identified to have significant therapeutic potential, especially in individuals with specific genetic variations.
The need to know
What are the benefits?
Supports sugar metabolism
Helps with brain fog
Protects against heart disease, liver disease and improves energy
Alpha lipoic acid is unique among antioxidants as it is both water- and fat-soluble, allowing it to work in various parts of the cell. It plays a role in the energy production process within cells by aiding the conversion of glucose into energy. Furthermore, ALA has been found to reduce the activation of NF-kB, thereby decreasing inflammation. This reduction in inflammation contributes to its protective effects against various diseases. One of ALA's standout features is its ability to recycle other antioxidants like vitamins C and E, enhancing the body's overall antioxidative defence. This is particularly crucial for individuals with genetic variants like SOD2, who might require increased antioxidant support. The involvement of ALA in numerous biochemical reactions helps improve energy metabolism, detoxification, and protection against oxidative stress.
How will I know its working?
Benefits may manifest as improved mental clarity, enhanced energy levels, and reduced inflammatory symptoms. Over time, tests may also show improved liver and heart function markers.
When to take it?
Take 1 tablet daily with food and water, unless specified otherwise on the sachet.
Serving Size 1 Vegetarian Capsule
Per Serving% Daily
Alpha Lipoic Acid
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.
Micro Crystalline Cellulose, Magnesium Stearate
Did you know?
Dietary Sources: Natural sources of alpha lipoic acid include the liver, kidney, spinach, and broccoli.
Dual Solubility: ALA is one of the few antioxidants that is both water and fat-soluble, making it versatile in its antioxidative actions within the body.
Recycling Role: ALA is pivotal in helping recycle other antioxidant vitamins like C and E, enhancing the body's overall defence against oxidative stress.
Publications you might find interesting
Want to go a bit deeper?
The latest research
1. Packer, L., Witt, E.H., and Tritschler, H.J. "Alpha-Lipoic acid as a biological antioxidant." *Free Radical Biology and Medicine* 19.2 (1995): 227-250.
2. Shay, K.P., Moreau, R.F., Smith, E.J., Smith, A.R., and Hagen, T.M. "Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential." *Biochimica et Biophysica Acta (BBA) - General Subjects* 1790.10 (2009): 1149-1160.
3. Rochette, L., Ghibu, S., Muresan, A., and Vergely, C. "Alpha-lipoic acid: molecular mechanisms and therapeutic potential in diabetes." *The Canadian Journal of Physiology and Pharmacology* 93.12 (2015): 1021-1027.
4. Biewenga, G.P., Haenen, G.R., and Bast, A. "The pharmacology of the antioxidant lipoic acid." *General Pharmacology: The Vascular System* 29.3 (1997): 315-331.
5. Gorąca, A., Huk-Kolega, H., Piechota, A., Kleniewska, P., Ciejka, E., and Skibska, B. "Lipoic acid - biological activity and therapeutic potential." *Pharmacological Reports* 63.4 (2011): 849-858.
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