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• Supports healthy sleep patterns and relaxation
• Essential for producing antioxidants like glutathione
• Aids energy production by promoting glycogen storage
Glycine may be the simplest amino acid in structure, but its impact on the body is profound. As a key building block of proteins, glycine plays a critical role in producing collagen, which supports skin elasticity, joint health, and wound healing. It is also essential for creating important molecules like glutathione, the body's master antioxidant that protects against oxidative stress and cellular damage.
Beyond its structural roles, glycine acts as a calming neurotransmitter in the brain, helping to regulate nerve signals and support mental relaxation. This makes it a powerful ally for promoting restful sleep and reducing anxiety. Glycine is also a cornerstone of energy metabolism, aiding in storing glycogen—a vital energy reserve for both physical and mental activity. Its versatility is unmatched, making glycine an essential amino acid for overall health and well-being.
• Glycine acts as a calming neurotransmitter in the brain, supporting nerve impulses and maintaining healthy sleep cycles.
• This versatile amino acid is essential for producing glutathione, DNA, creatine, bile, hemoglobin, and other proteins.
• Glycine enhances glycogen storage, ensuring glucose is readily available for energy product
The science behind glycine’s benefits is as multifaceted as its functions in the body.
Sleep and Relaxation
Glycine works as an inhibitory neurotransmitter, calming overactive nerve impulses in the central nervous system. It influences the hypothalamus, a brain region that controls body temperature and sleep-wake cycles, helping your body prepare for restful sleep. Clinical studies have shown that glycine supplementation can improve sleep quality, reduce time to fall asleep, and enhance cognitive performance the following day—even in sleep-deprived individuals.
Antioxidant and Detoxification Support
As a precursor to glutathione, glycine is indispensable for the body’s detoxification processes. Glutathione neutralizes harmful free radicals, supports liver function, and protects cells from oxidative damage. A glycine-rich diet or supplementation helps replenish glutathione levels, particularly under stress or during illness.
Energy Production and Metabolism
Glycine plays a role in glycogen storage, which is critical for maintaining blood sugar balance and ensuring a steady energy supply. It also contributes to ATP production—the body’s primary energy currency—by aiding mitochondrial function, making it a valuable supplement for those with high physical or mental demands.
Collagen Synthesis and Tissue Repair
Glycine accounts for a third of the amino acids in collagen, the protein that maintains the structure and integrity of skin, joints, and connective tissues. Regular glycine intake supports joint flexibility, wound healing, and skin elasticity, slowing down the visible signs of aging.
Brain Health and Cognitive Support
Beyond sleep, glycine supports brain health by modulating neurotransmitter activity and reducing neural inflammation. Emerging research suggests glycine could play a role in protecting against cognitive decline, making it a promising area for further investigation.
You may notice more restful sleep, reduced fatigue, and improved mental clarity.
Take 1-3 capsules at night before bed to improve sleep.
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.
Hypromellose (cellulose capsule), Hydroxypropyl Cellulose, Stearic Acid (vegetable source) and Silicon Dioxide.
1. Bannai M, Kawai N, Ono K, Nakahara K, Murakami N. The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Front Neurol. 2012 Apr 18;3:61. doi: 10.3389/fneur.2012.00061. PMID: 22529837; PMCID: PMC3328957.
2. Imenshahidi M, Hossenzadeh H. Effects of glycine on metabolic syndrome components: a review. J Endocrinol Invest. 2022 May;45(5):927-939. doi: 10.1007/s40618-021-01720-3. Epub 2022 Jan 11. PMID: 35013990.
3. Kawai N, Sakai N, Okuro M, Karakawa S, Tsuneyoshi Y, Kawasaki N, Takeda T, Bannai M, Nishino S. The sleep-promoting and hypothermic effects of glycine are mediated by NMDA receptors in the suprachiasmatic nucleus. Neuropsychopharmacology. 2015 May;40(6):1405-16. doi: 10.1038/npp.2014.326. Epub 2014 Dec 23. PMID: 25533534; PMCID: PMC4397399.
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• Supports cellular health and longevity
• Boosts NAD function
• Promotes skin health and elasticity