Glutathione is a tripeptide composed of three amino acids: cysteine, glutamate, and glycine. It is naturally produced in the liver and found in various cells throughout the body. Often referred to as the "master antioxidant," glutathione plays a crucial role in detoxification and immune function.
Roles & Functions
Antioxidant Defense: Glutathione neutralizes harmful free radicals, protecting cells from oxidative stress and potential damage.
Detoxification: It binds to toxins and heavy metals in the liver, aiding in their removal from the body.
Immune System Support: Glutathione enhances the activity of immune cells and plays a part in the body’s natural defense mechanisms against pathogens.
The need to know
What are the benefits?
Detoxification master molecule
Redox Balance: Glutathione exists in reduced (GSH) and oxidized (GSSG) states. The ratio of these forms maintains the cellular redox status, essential for many biological processes.
Cysteine Donor: Glutathione donates its cysteine thiol group, which is essential in biochemical reactions that neutralise free radicals or detoxify harmful substances.
Enzyme Cofactor: It works as a cofactor for various antioxidant enzymes like glutathione peroxidase, catalysing the conversion of harmful peroxides to water.
Glutathione and health
Chronic Disease: Lower glutathione levels are associated with several chronic conditions such as neurodegenerative diseases, cardiovascular diseases, and certain types of cancers.
Ageing: Glutathione levels naturally decrease with age, making supplementation or dietary intake beneficial for maintaining good health.
How will I know its working?
Increased energy, improved skin complexion, and a more robust immune response (fewer illnesses) can be indicators.
When to take it?
Take 1 capsule daily with food and water, unless specified otherwise on the sachet.
Per Serving% Daily
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.
1. L-glutathione is often referred to as the "master antioxidant" in the body, combating oxidative stress and neutralizing harmful free radicals.
2. It plays a crucial role in detoxifying the liver, helping eliminate toxins and supporting overall liver health.
3. L-glutathione has gained attention for its potential skin-lightening properties and its ability to reduce signs of ageing by combating oxidative damage to skin cells.
Publications you might find interesting
Want to go a bit deeper?
The latest research
1. Pizzorno, J. ""Glutathione!"". Integrative Medicine (Encinitas) 13.1 (2014): 8-12.
2. Wu, G., Fang, Y.Z., Yang, S., Lupton, J.R., & Turner, N.D. ""Glutathione metabolism and its implications for health."" The Journal of nutrition 134.3 (2004): 489-492.
3. Sekhar, R.V., Patel, S.G., Guthikonda, A.P., Reid, M., Balasubramanyam, A., Taffet, G.E., & Jahoor, F. ""Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation."" The American journal of clinical nutrition 94.3 (2011): 847-853.
4. Witschi, A., Reddy, S., Stofer, B., & Lauterburg, B.H. ""The systemic availability of oral glutathione."" European journal of clinical pharmacology 43.6 (1992): 667-669.
5. Sonthalia, S., Daulatabad, D., & Sarkar, R. ""Glutathione as a skin whitening agent: Facts, myths, evidence and controversies."" Indian Journal of Dermatology, Venereology, and Leprology 82.3 (2016): 262.
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