Dr Geoff's Longevity stack

Ageing isn't just the passage of time; it's the culmination of damage at a cellular and molecular level, and we now have the means to address this.

Sirtuins, proteins that regulate cellular health, were first discovered in yeast but have since been identified as major players in human longevity.

AMPK, often dubbed the "master metabolic switch", orchestrates energy balance in our cells, and its activation can mimic the benefits of calorie restriction, a known longevity enhancer.

NMN. The humanpeople NMN is 99.5% pure B-nicotinamide mononucleotide (“NMN”), which is highly absorbable in the gut. It increases energy production and activates sirtuins. It increases AMPK and enhances cell energy production.

Urolithin A: Metabolite that improves mitochondrial function by inducing mitophagy, the removal of damaged mitochondria.

Spermidine: Induces autophagy, a cellular recycling process that removes damaged components, enhancing cellular function and longevity.

Resveratrol (trans form) works by activating sirtuin pathways. Trans-resveratrol is the most active form and works synergistically with NMN. It also increases NAD+ levels by activating the NMNAT1 enzyme up to 5-fold in neurons.

Coenzyme Q10 is a commonly used cofactor because it is essential as a mitochondrial electron transporter and acting as an antioxidant. It delays brain atrophy, and a blinded study showed that within 8 days, the participants on CoQ10 were able to cycle further with lower fatigue.

B vitamins: Synthesis of CoQ10 is dependent on vitamins B2 (riboflavin) and vitamins B6 (pyridoxal-phosphate), folate (vitamin B9), pantothenic acid (vitamin B5), niacin (vitamin B3) and vitamin C.

Vitamins D3, K2, and Methylated B Complex: These vital nutrients offer holistic support, from bone health to metabolic processes and cellular energy synthesis.

Curated by doctors for synergistic effect. Each component is pharma-grade, research-dosed, and backed by published evidence with a clear clinical rationale. Made to GMP standards, ensuring purity, consistency, and traceability. Each dose is prepared in ready-to-use sachets to create a daily routine that’s effortless and easy to follow.