TUDCA

Name: TUDCA
Brand: humanpeople
SKU: 1000100155
Price: 26.5 GBP
Availability: InStock

TUDCA

500mg

£26.50

28 day supply (£0.94 / day)

£26.50

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Product variants

• Bile acid supporting liver detoxification

• Supports mould excretion and gut health

• Neuroprotection

Quantity

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The basics

Tauroursodeoxycholic Acid (TUDCA) is a bile acid naturally produced in small amounts in the human body. It supports various physiological functions, including digestion, brain health, cellular protection, and detoxification.
Key Benefits of TUDCA
Liver Health and Detoxification: TUDCA supports bile flow and liver function, aiding in the removal of toxins and improving conditions like fatty liver disease and cholestasis. It also lowers liver enzyme levels, indicating reduced inflammation and damage.
Cellular and Mitochondrial Support: TUDCA stabilises mitochondria, reduces oxidative stress, and prevents premature apoptosis (cell death). These effects enhance energy production and protect cells from damage caused by toxins, stress, and metabolic dysregulation.
Gut and Microbiome Support: It strengthens gut barrier integrity, reducing leaky gut and supporting healthy gut microbiota. TUDCA also promotes bile acid balance, critical for fat digestion and pathogen defense.

The need to know

What are the benefits?

TUDCA supports liver health, cellular protection, mitochondrial function, and gut integrity, making it a powerful supplement for detoxification, metabolic balance, and overall systemic resilience.

The Science

The Science Behind TUDCA
Liver Health:

TUDCA supports liver function by improving bile acid flow, reducing toxic bile accumulation, and protecting hepatocytes from damage caused by fatty liver disease, cholestasis, and drug-induced liver injury.
It works as a chaperone molecule to reduce ER stress, which is a major contributor to liver dysfunction.
Digestive Support:

By enhancing bile salt secretion, TUDCA helps with fat digestion and absorption. It can be particularly helpful for those with gallbladder issues or sluggish bile flow.
Anti-Inflammatory Effects:

TUDCA has been shown to reduce inflammation in the liver and other tissues by modulating inflammatory pathways, including NF-kB.
Neuroprotective Benefits:

TUDCA has been studied for its ability to protect neurons and reduce oxidative stress in the brain. Emerging research indicates its potential in managing conditions like Alzheimer's, Parkinson's, and Huntington's diseases.
Metabolic Health:

TUDCA improves insulin sensitivity and reduces inflammation in metabolic conditions such as diabetes and obesity.

How will I know its working?

Beneficial in supporting detoxification and management of mold and mycotoxin issues.

When to take it?

Use 2 capsules up to twice a day as directed.

Ingredients

Supplement Facts

Ingredient Amount
Per Serving % Daily
Value

Tauroursodeoxycholic Acid 500mg
†

* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.

Bulking Agent (Rice Flour), Gelatine Capsule.

Did you know?

Publications you might find interesting

Want to go a bit deeper?

The latest research

1. Zheng X, Cao J, Wang H, Liu L, Jin B, Zhang H, Li M, Nian S, Li H, He R, Wang N, Li X, Wang K. Effects of tauroursodeoxycholate on arsenic-induced hepatic injury in mice: A comparative transcriptomic analysis. J Trace Elem Med Biol. 2024 Aug 28;86:127512. doi: 10.1016/j.jtemb.2024.127512. Epub ahead of print. PMID: 39232337.
2. Zangerolamo L, Vettorazzi JF, Rosa LRO, Carneiro EM, Barbosa HCL. The bile acid TUDCA and neurodegenerative disorders: An overview. Life Sci. 2021 May 1;272:119252. doi: 10.1016/j.lfs.2021.119252. Epub 2021 Feb 23. PMID: 33636170.
3, Li J, Huang Z, Jin Y, Liang L, Li Y, Xu K, Zhou W, Li X. Neuroprotective Effect of Tauroursodeoxycholic Acid (TUDCA) on In Vitro and In Vivo Models of Retinal Disorders: A Systematic Review. Curr Neuropharmacol. 2024;22(8):1374-1390. doi: 10.2174/1570159X21666230907152207. PMID: 37691227; PMCID: PMC11092919.
4. Lombardo FL, Spila Alegiani S, Mayer F, Cipriani M, Lo Giudice M, Ludolph AC, McDermott CJ, Corcia P, Van Damme P, Van den Berg LH, Hardiman O, Nicolini G, Vanacore N, Dickie B, Albanese A, Puopolo M; TUDCA-ALS Study Group. A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial. Trials. 2023 Dec 5;24(1):792. doi: 10.1186/s13063-023-07638-w. PMID: 38053196; PMCID: PMC10696667.