GLP-1 Inflammation & resistin support

This stack targets “inflammatory metabolic resistance” the physiology of patients who have normal glucose and insulin but high resistin, leptin, and NEFA, indicating fat-cell stress and inflammation rather than insulin resistance.
It works through three integrated mechanisms:
Reduce inflammation and oxidative stress

→ NAC, omega-3, and alpha-lipoic acid restore glutathione and reduce NF-κB signalling.

Improve mitochondrial energy and fat transport.

→ NR and L-carnitine increase NAD⁺ and fatty-acid β-oxidation capacity.

Enhance metabolic signalling and nutrient sensitivity.

→ Resveratrol and chromium improve AMPK and adiponectin activity; inositol improves cellular signalling and cortisol balance.

Together, these mechanisms help GLP-1 therapy work more effectively, improving energy, reducing side effects, and promoting fat loss from the right tissues.

1. Anti-inflammatory and antioxidant defence
N-acetyl-L-cysteine (NAC) replenishes intracellular glutathione and directly suppresses TNF-α and IL-6, both linked to elevated resistin.
Alpha-lipoic acid (ALA) acts as a cofactor for mitochondrial enzymes and regenerates antioxidants (vitamin C, E, CoQ10). Trials show ALA lowers CRP and HOMA-IR while improving lipid oxidation.
Omega-3 fatty acids (EPA/DHA) down-regulate NF-κB and reduce circulating resistin and CRP by up to 30 % in metabolic-syndrome cohorts.


2. NAD⁺ and mitochondrial metabolism
Nicotinamide riboside (NR) boosts NAD⁺, supporting mitochondrial sirtuin activity (SIRT1, SIRT3) and AMPK activation key in controlling adipose inflammation.
L-carnitine transports long-chain fatty acids into mitochondria, preventing NEFA accumulation that perpetuates inflammation and insulin resistance.
Alpha-lipoic acid complements this by facilitating pyruvate dehydrogenase and improving mitochondrial redox status.
3. Metabolic and hormonal signalling
Inositol (×2) improves adiponectin and insulin signalling, reducing cortisol-related inflammation.
Chromium (×1) supports normal blood glucose and enhances insulin receptor sensitivity.
Liposomal resveratrol activates SIRT1 and AMPK pathways similar to caloric restriction, suppressing inflammatory cytokines and promoting mitochondrial biogenesis.
The Athletic & Brain complex adds B vitamins, CoQ10, and vitamin D/K2 to support energy metabolism and neurocognitive function during metabolic repair.

Take sachets with food, they can be taken am or pm but we recommend not later than 6pm as they can increase energy levels.

Reducing inflammation and supporting fat burning has a significant impact on mental and physical energy and recovery. After a few weeks you may notice improve concentration and drive.