
GLP-1 support insulin & fat resistance reset
GLP-1 support insulin & fat resistance reset
• Targets insulin and leptin resistance, not just calories.
• Supports fat metabolism, cravings control, and steady energy.
• Doctor-designed; pairs with GLP protocols and blood‑test monitoring.








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GLP-1 support insulin & fat resistance reset
This combination of supplements has been clinically proven to optimise results through its synergistic effects.
The Benefits of this combination
Steadier energy and fewer post‑meal crashes within 2–4 weeks.
Reduced cravings for fast‑release carbs as protein and fat metabolism improve.
Triglycerides trend down; insulin sensitivity markers often improve when paired with diet and activity.
Even if you’re eating less, insulin resistance in your fat cells (aka Adipo-IR) can block fat from being released.
Your body still needs energy but if it can’t access fat, it burns muscle instead.
That’s why some people lose weight on the scale but feel weak, tired, and never see real body composition change.
Fat isn’t just storage it’s an active endocrine organ.
When healthy, your fat cells produce adiponectin, which helps burn fat and improve insulin sensitivity.
But in fat resistance, these same cells start pumping out inflammatory hormones (like resistin and TNF-alpha) that lock in fat and promote insulin resistance system-wide.
High Adipo-IR is one of the biggest reasons GLP-1 medications stop working or backfire.
If fat cells are resistant to insulin, they can’t release fat properly even when appetite drops.
That’s why people with high Adipo-IR often plateau on GLPs, then regain fat when they come off unless the root metabolic issue is treated..
The need to know

What is it?
Insulin resistance means your cells ignore insulin’s signal, so sugar stays in the blood and fat stays locked in fat cells. Leptin resistance means your brain can’t “hear” the full signal from body fat, so hunger and cravings can feel louder than they should. This pack aims to:
Calm inflammation and improve membrane signalling (omega‑3, vitamin d3+k2).
Support insulin pathways and glucose transport (inositol, ala, magnesium).
Boost cellular energy use and fat transport.
The Science
GLPs alone aren’t enough
GLP-1s reduce appetite and food intake, but do not directly correct:
Insulin resistance, especially in adipose tissue (Adipo-IR)
Leptin resistance, which impairs satiety and fat signalling
Low adiponectin, which reduces fat oxidation
Inflammatory adipokines like resistin and TNF-α
These are the real root drivers of fat loss resistance.
High Adipo-IR = Metabolic Block
Patients with high Adipo-IR have fat cells that are insulin-resistant. This blocks lipolysis the breakdown and release of fat and causes:
Preferential muscle catabolism
Fat stored in visceral depots
Reduced metabolic flexibility
Even on GLPs, these patients often plateau, regain fat later, or experience metabolic rebound.
When to take it?
Take the supplement pack daily with food and water, before morning or afternoon meal, unless specified otherwise on the sachet.
What are the benefits?
Steadier energy and fewer post‑meal crashes within 2–4 weeks.
Reduced cravings for fast‑release carbs as protein and fat metabolism improve.
Triglycerides trend down; insulin sensitivity markers often improve when paired with diet and activity.
Ingredients
See individual supplements for further ingredient details.
Vitamin B1 (Thiamine Hcl) 25mg 2272%
Vitamin B2 (Riboflavin 5'Phosphate) 10mg 714%
Vitamin B3 (Niacin) 25mg 156%
Vitamin B5 (Pantothenic Acid) 25mg 416%
Vitamin B6 (Pyridoxal 5'Phosphate) 10mg 714%
Vitamin B12 (Hydroxocobalamin) 1,000mcg 40,000%
Folate (L-5-MTHF) 800mcg 400%
Biotin 500mcg 1000%
Vitamin D3 (4,000IU) 100mcg 2000%
Vitamin K2 (MK-7) 250mcg 332%
CoQ10 100mg
BioPerine (Black Pepper Extract) 5mg
NR: 500mg
Omega-3: 1000mg EPA 330mg DHA 220mg
Magnesium (1000mg from Magnesium Lysinate Glycinate Chelate) 100mg 25%
Alpha-lipoic acid: 350mg
Inositol: 1300mg
Alpha-lipoic acid: 350mg
Chromium picolinate: 1000mcg
Essential mineral & vitamin:
Vitamin A 400µg 50.00%
Vitamin D3 12.5µg 250%
Vitamin E a-TE 12.5µg 50%
Vitamin K2 37.5µg 50.00%
Vitamin C 40mg 50.00%
Vitamin B1 0.55mg 50.00%
Vitamin B2 1.4mg 100.00%
Vitamin B3 8mg 50.00%
Vitamin B6 1.1mg 75.00%
Folic Acid 200µg 100.00%
Vitamin B12 12.5µg 500.00%
Biotin 25µg 50.00%
Vitamin B5 3mg 50.00%
Calcium 234mg 29.25%
Phosphorus 40mg 3.00%
Magnesium 94mg 25.00%
Iron 7mg 50.00%
Zinc 7.5mg 75.00%
Copper 0.5mg 50.00%
Manganese 1mg 50.00%
Selenium 30µg 54.50%
Chromium 10µg 25.00%
Molybdenum 12.5µg 25.00%
Iodine 75µg 50.00%
frequently asked questions
FAQ
Can I combine different packs?
Yes. The simple way to combine packs is to just add them to your cart. If you are already a user make sure you are logged in and this will be checked against our current stack. We will show you were the duplicates are so you only add the ones you want.
Can I add other supplements to the pack?
Yes. Just add the pack and continue browsing. You can look at the other packs we have put together or view all of our supplements here.
If I subscribe to a product can I cancel it?
Yes. We make it easy to pause, change your subscription date or cancel. For some supplements it may take 1-2 weeks to feel the benefit. Check how you feel physically, mentally and after exercise. Sometimes we miss these subtle improvements.
Are your products made in the UK?
Yes all our supplements are made in the UK at GMP facilities.
Are all your products third party tested?
For simple supplements like vitamin D or B12 these are all tested in house by our manufacturers. For advanced longevity supplements like NMN we test these in an independent UK certified lab. We publish many of these certificates on our website.
Can I remove some products from the pack?
Yes of course. We are here to guide you to optimal combinations but the choice is yours.

Integrated Solutions
If you want a more personalised approach consider our blood and DNA testing. Our in house Doctors will then provide you with personalised recommendations.
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