
GLP-1 support insulin & fat resistance reset
GLP-1 support insulin & fat resistance reset
• Targets insulin and leptin resistance, not just calories.
• Supports fat metabolism, cravings control, and steady energy.
• Doctor-designed; pairs with GLP protocols and blood‑test monitoring.








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GLP-1 support insulin & fat resistance reset
This combination of supplements has been clinically proven to optimise results through its synergistic effects.
The Benefits of this combination
Steadier energy and fewer post‑meal crashes within 2–4 weeks.
Reduced cravings for fast‑release carbs as protein and fat metabolism improve.
Triglycerides trend down; insulin sensitivity markers often improve when paired with diet and activity.
Even if you’re eating less, insulin resistance in your fat cells (aka Adipo-IR) can block fat from being released.
Your body still needs energy but if it can’t access fat, it burns muscle instead.
That’s why some people lose weight on the scale but feel weak, tired, and never see real body composition change.
Fat isn’t just storage it’s an active endocrine organ.
When healthy, your fat cells produce adiponectin, which helps burn fat and improve insulin sensitivity.
But in fat resistance, these same cells start pumping out inflammatory hormones (like resistin and TNF-alpha) that lock in fat and promote insulin resistance system-wide.
High Adipo-IR is one of the biggest reasons GLP-1 medications stop working or backfire.
If fat cells are resistant to insulin, they can’t release fat properly even when appetite drops.
That’s why people with high Adipo-IR often plateau on GLPs, then regain fat when they come off unless the root metabolic issue is treated..
The need to know

What is it?
Insulin resistance means your cells ignore insulin’s signal, so sugar stays in the blood and fat stays locked in fat cells. Leptin resistance means your brain can’t “hear” the full signal from body fat, so hunger and cravings can feel louder than they should. This pack aims to:
Calm inflammation and improve membrane signalling (omega‑3, vitamin d3+k2).
Support insulin pathways and glucose transport (inositol, ala, magnesium).
Boost cellular energy use and fat transport.
The Science
GLPs alone aren’t enough
GLP-1s reduce appetite and food intake, but do not directly correct:
Insulin resistance, especially in adipose tissue (Adipo-IR)
Leptin resistance, which impairs satiety and fat signalling
Low adiponectin, which reduces fat oxidation
Inflammatory adipokines like resistin and TNF-α
These are the real root drivers of fat loss resistance.
High Adipo-IR = Metabolic Block
Patients with high Adipo-IR have fat cells that are insulin-resistant. This blocks lipolysis the breakdown and release of fat and causes:
Preferential muscle catabolism
Fat stored in visceral depots
Reduced metabolic flexibility
Even on GLPs, these patients often plateau, regain fat later, or experience metabolic rebound.
When to take it?
Take the supplement pack daily with food and water, before morning or afternoon meal, unless specified otherwise on the sachet.
What are the benefits?
Steadier energy and fewer post‑meal crashes within 2–4 weeks.
Reduced cravings for fast‑release carbs as protein and fat metabolism improve.
Triglycerides trend down; insulin sensitivity markers often improve when paired with diet and activity.
Ingredients
See individual supplements for further ingredient details.
Vitamin B1 (Thiamine Hcl)
Vitamin B2 (Riboflavin 5'Phosphate)
Vitamin B3 (Niacin)
Vitamin B5 (Pantothenic Acid)
Vitamin B6 (Pyridoxal 5'Phosphate)
Vitamin B12 (Hydroxocobalamin)
Folate (L-5-MTHF)
Biotin
Vitamin D3 (4,000IU)
Vitamin K2 (MK-7)
CoQ10
BioPerine (Black Pepper Extract)
Vitamin A 800ug
Vitamin E a-TE 12mg
Vitamin K2 75µg
Vitamin C 80mg
Vitamin B1 1.1mg
Vitamin B2 2.8mg
Vitamin B3 16mg
Vitamin B6 2.1mg
Folic Acid 400µg
Vitamin B12 25 µg
Biotin 50µg
Vitamin B5 6mg
Calcium 468mg
Phosphorus 80mg
Magnesium 187.5mg
Iron 14mg
Zinc 15 mg
Copper 1mg
Manganese 2mg
Selenium 60µg
Chromium 20 µg
Molybdenum 25µg
Iodine 150 µg
Magnesium glycinate 1000mg
Chromium picolinate 1000mcg
Omega-3 1000mg
NR nicotinamide riboside 500mg
Acetyl L-carnitine 500mg
Alpha lipoic acid 300mg
Inositol 1300mg
frequently asked questions
FAQ
Can I combine different packs?
Yes. The simple way to combine packs is to just add them to your cart. If you are already a user make sure you are logged in and this will be checked against our current stack. We will show you were the duplicates are so you only add the ones you want.
Can I add other supplements to the pack?
Yes. Just add the pack and continue browsing. You can look at the other packs we have put together or view all of our supplements here.
If I subscribe to a product can I cancel it?
Yes. We make it easy to pause, change your subscription date or cancel. For some supplements it may take 1-2 weeks to feel the benefit. Check how you feel physically, mentally and after exercise. Sometimes we miss these subtle improvements.
Are your products made in the UK?
Yes all our supplements are made in the UK at GMP facilities.
Are all your products third party tested?
For simple supplements like vitamin D or B12 these are all tested in house by our manufacturers. For advanced longevity supplements like NMN we test these in an independent UK certified lab. We publish many of these certificates on our website.
Can I remove some products from the pack?
Yes of course. We are here to guide you to optimal combinations but the choice is yours.

Integrated Solutions
If you want a more personalised approach consider our blood and DNA testing. Our in house Doctors will then provide you with personalised recommendations.
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