GLP-1 Core rebuild: Metabolic Tone (men)

Core Rebuild GLP+ (for him) is a daily metabolic stack for men with visceral fat and central weight gain, especially when using GLP-1 medication or a structured weight-loss programme.
Inositol + chromium + B vitamins support normal insulin function and blood glucose control, which is key when appetite is reduced but metabolic load is still high.

L-carnitine, alpha-lipoic acid and omega-3 work together around the mitochondria: transporting fatty acids into the “energy furnace”, supporting insulin sensitivity and helping maintain a healthier lipid profile.

NR, vitamin D3/K2 and the essential mineral + vitamin complex underpin NAD⁺-dependent energy metabolism, hormone signalling and cardiovascular health.

The aim is not just to lose weight, but to rebuild metabolic capacity: better fat handling, more efficient mitochondria, and a more robust cardiometabolic profile for men with deep belly fat.

Visceral fat acts as an endocrine organ that releases inflammatory cytokines and free fatty acids, disrupting insulin and hormone signalling. This stack supports mitochondrial function and testosterone production to counter those effects.

Inositol is a key signalling molecule in insulin pathways. Systematic reviews suggest that inositol can improve markers of insulin resistance and lipid profiles in at-risk individuals, including those with metabolic syndrome. In men with visceral adiposity, the goal is to support insulin sensitivity upstream rather than relying purely on GLP-1–driven appetite reduction.

• Chromium contributes to the maintenance of normal blood glucose levels. It supports insulin action at the receptor level, helping the body handle carbohydrates more efficiently during GLP-1 therapy or a calorie deficit.

• Vitamin D contributes to normal muscle function, immune function and the maintenance of normal bones, while vitamin K contributes to normal blood clotting and bone maintenance. Adequate vitamin D is also associated with improved muscle performance and metabolic health in men with central obesity. In the GLP-1 setting, this helps protect musculoskeletal health as weight comes off.

• NR – nicotinamide riboside) A precursor to NAD⁺, a central cofactor in mitochondrial energy production and cellular repair. Supporting NAD⁺ helps maintain energy, mitochondrial function and metabolic flexibility during weight-loss phases, when low energy intake can otherwise push the system towards fatigue rather than regeneration.

• Omega-3 fatty acids contribute to normal heart and brain function and help reduce inflammation that can increase with declining hormones.

• Alpha-lipoic acid (ALA) improves mitochondrial function and reduces oxidative stress, helping sustain testosterone synthesis.

• Liposomal resveratrol (×1) A polyphenol associated with healthy ageing pathways and vascular function. In liposomal form, it has improved bioavailability. Combined with NR, it complements NAD⁺ support and may help maintain endothelial health and metabolic signalling during GLP-1-assisted weight loss.

• Magnesium glycinate supports more than 300 enzyme systems, aiding glucose control, energy release, and muscle relaxation valuable where GLP-1 therapy may reduce dietary magnesium intake.

• L-carnitine shuttles long-chain fatty acids into mitochondria, where they can be oxidised for energy. Human studies have shown that increasing muscle carnitine content can enhance fat oxidation, improve exercise metabolism, and even prevent fat gain when calories are high

Together, these nutrients help men sustain metabolic efficiency, reduce hidden fat, and preserve lean mass while using or transitioning off GLP-1 therapy.

Take two sachets daily, preferably with meals or as directed by your practitioner. Use for 12 weeks or longer to maintain energy and reduce hidden fat.

Within 4-8 weeks you may notice better energy, improved focus, and flatter abdominal contour. Blood tests may show improved triglycerides, insulin, and testosterone balance.